Steven R Lentz Selected Research

Carotid Artery Thrombosis

1/2020	Targeting Myeloid-Specific Integrin α9β1 Improves Short- and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation.
12/2015	Genetic Ablation of Extra Domain A of Fibronectin in Hypercholesterolemic Mice Improves Stroke Outcome by Reducing Thrombo-Inflammation.
8/2015	Deficiency of superoxide dismutase impairs protein C activation and enhances susceptibility to experimental thrombosis.
5/2015	Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4.
1/2014	Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia.
10/2006	Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia.

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Steven R Lentz Research Topics

Disease

31	Thrombosis (Thrombus) 01/2021 - 01/2002
25	Hyperhomocysteinemia 01/2020 - 09/2002
13	Hemophilia A (Haemophilia) 02/2022 - 07/2011
10	Atherosclerosis 01/2018 - 08/2002
9	Hemorrhage 02/2022 - 05/2016
9	Inflammation (Inflammations) 01/2020 - 07/2004
8	Venous Thromboembolism 01/2019 - 09/2004
6	Carotid Artery Thrombosis 01/2020 - 10/2006
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 07/2004
6	Vascular Diseases (Vascular Disease) 01/2017 - 04/2004
5	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021 - 03/2012
5	Stroke (Strokes) 01/2020 - 09/2004
4	Ischemic Stroke 01/2020 - 05/2012
4	Reperfusion Injury 01/2020 - 05/2012
4	Hypertension (High Blood Pressure) 01/2017 - 04/2008
3	Hyperplasia 01/2021 - 12/2015
3	Vascular System Injuries 01/2020 - 12/2015
3	Infarction (Infarctions) 01/2020 - 01/2014
3	Obesity 12/2016 - 09/2013
3	Hypercholesterolemia 12/2015 - 01/2007
3	Atherosclerotic Plaque (Atheroma) 11/2015 - 01/2007
2	COVID-19 01/2022 - 01/2021
2	Virus Diseases (Viral Diseases) 01/2022 - 07/2003
2	Homocystinuria 01/2020 - 07/2004
2	Hemophilia B (Haemophilia B) 11/2018 - 05/2016
2	Thrombophilia 07/2017 - 03/2013
2	Morbid Obesity 12/2016 - 11/2016
2	Brain Ischemia (Cerebral Ischemia) 01/2016 - 05/2012
2	Pulmonary Embolism 01/2015 - 05/2002
2	Myocardial Infarction 01/2014 - 09/2004
2	Fatty Liver 03/2010 - 12/2007
2	Alzheimer Disease (Alzheimer's Disease) 03/2007 - 07/2004
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022
1	Reinfection 01/2022
1	Intractable Pain 01/2022

Drug/Important Bio-Agent (IBA)

13	Methionine (L-Methionine)FDA Link 01/2017 - 10/2006
12	HomocysteineIBA 01/2020 - 07/2004
9	AnticoagulantsIBA 10/2018 - 08/2002
9	Folic Acid (Vitamin M)FDA LinkGeneric 01/2017 - 04/2006
8	EnzymesIBA 01/2022 - 07/2004
8	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 01/2020 - 09/2002
8	Apolipoproteins E (ApoE)IBA 01/2020 - 07/2004
8	ApolipoproteinsIBA 01/2018 - 07/2004
7	Protein CIBA 07/2017 - 08/2002
6	Factor VIII (Coagulation Factor VIII)IBA 05/2020 - 01/2017
6	Fibronectins (Fibronectin)IBA 01/2020 - 05/2012
6	Proteins (Proteins, Gene)FDA Link 07/2017 - 03/2007
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2010 - 12/2003
5	recombinant factor VIII N8IBA 02/2022 - 01/2017
4	FibrinIBA 01/2020 - 12/2015
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 11/2004
4	von Willebrand FactorIBA 07/2019 - 03/2012
4	Superoxides (Superoxide)IBA 01/2019 - 08/2004
4	recombinant FVIIa (rFVIIa)FDA Link 04/2017 - 05/2002
4	human extra domain A fibronectinIBA 12/2015 - 05/2012
4	ThrombomodulinIBA 08/2015 - 01/2003
4	Nitric Oxide Synthase (NO Synthase)IBA 02/2010 - 07/2005
3	Hemostatics (Antihemorrhagics)IBA 02/2022 - 01/2002
3	Pyruvate KinaseIBA 01/2022 - 01/2021
3	LigandsIBA 01/2020 - 11/2004
3	fibrin fragment D (D-dimer)IBA 01/2019 - 01/2015
3	Thrombin FDA Link 01/2018 - 08/2002
3	Metalloproteases (Metalloproteinases)IBA 01/2017 - 08/2009
3	Biomarkers (Surrogate Marker)IBA 12/2016 - 01/2007
3	Toll-Like Receptor 4IBA 11/2015 - 05/2012
3	S-AdenosylhomocysteineIBA 03/2010 - 07/2005
3	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 02/2010 - 07/2005
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2022 - 01/2016
2	IntegrinsIBA 01/2020 - 01/2016
2	AntibodiesIBA 01/2020 - 04/2015
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2019 - 01/2018
2	Factor IX (Coagulation Factor IX)FDA LinkGeneric 11/2018 - 05/2016
2	nonacog beta pegolIBA 11/2018 - 05/2016
2	factor V LeidenIBA 07/2017 - 01/2002
2	Prothrombin (Factor II)IBA 07/2017 - 05/2002
2	Urea (Carbamide)FDA LinkGeneric 01/2017 - 03/2010
2	Superoxide DismutaseIBA 01/2017 - 08/2015
2	Superoxide Dismutase-1IBA 01/2017 - 08/2015
2	estropipate (Ogen)FDA LinkGeneric 01/2017 - 12/2015
2	InterleukinsIBA 12/2015 - 11/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2015 - 04/2008
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 04/2015 - 05/2013
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 03/2013 - 04/2008
2	AntioxidantsIBA 03/2013 - 03/2010
2	Glutathione (Reduced Glutathione)IBA 03/2013 - 04/2008
2	S-Adenosylmethionine (Ademetionine)IBA 03/2010 - 07/2005
2	dimethylargininaseIBA 02/2010 - 08/2008
2	Glutathione PeroxidaseIBA 04/2008 - 12/2002
2	Phospholipids (Phosphatides)FDA LinkGeneric 12/2007 - 01/2007
1	Angiotensin-Converting Enzyme 2IBA 01/2022
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2022
1	Liposomes (Liposome)IBA 01/2022
1	Hemoglobins (Hemoglobin)IBA 01/2022

Therapy/Procedure

10	Therapeutics 01/2021 - 09/2004
3	Injections 05/2019 - 01/2017
3	Ligation 12/2015 - 03/2012
2	Lasers (Laser) 01/2021 - 01/2020
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/2015 - 05/2015
1	Orthopedic Procedures 01/2022
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2022